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Which one of the following conditions though harmful in itself, is also a potential  saviour from a mosquito borne infectious disease?

Hi, I have a question and I hope anyone could answer it:

Which one of the following conditions though harmful in itself, is also a potential  saviour from a mosquito borne infectious disease?

  (a) Pernicious anaemia

 (b) Leukaemia

 (c) Thalassemia

 (d) Sickle-cell anaemia

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